Highly-talented Kapuso actress Kris Bernal takes on the role of Rachel. She is beautiful, simple, and dreams of having a happy family. Rachel meets Nathan, a smart businessman from a political family. Nathan marries Rachel out of pressure from his conservative family but he is unhappy and feels trapped. Deep down, he always knew he was gay, so he devised a way to fake his death. The truth is he went abroad and took their daughter with him. He undergoes sexual reassignment and facial feminization surgery in order to fully embrace the woman inside him. He left without knowing that Rachel is pregnant with their second child. Rachel, after Nathan died, went to the province where she gave birth.

Years later, Rachel meets the good-looking balikbayan Gavin, portrayed by returning Kapuso Rayver Cruz as he stars in his very first drama series in the Network. Rachel falls for him instantly but her prospect of happiness is met with a big blow when she discovers that he’s engaged to a mysterious and strikingly beautiful woman named Venus, breathed to life by Thea Tolentino. Venus is also a single mother who said that she got pregnant from her previous relationship/

Rachel feels that something isn’t quite right with Venus. Eventually, she found out the truth: Venus is a sexually reassigned woman who is no other than her former husband, Nathan.

Former husband and wife, now both fighting for the love of the same man. This is the intriguing and captivating premise of Asawa Ko, Karibal Ko.

Playing a very special role in the series is Kapuso actor Jason Abalos as Nathan, Rachel’s husband and a woman trapped inside a woman’s body.